Total STAMP2 Cell-Based Colorimetric ELISA Kit
- 货号：KA3792C
- 应用：ELISA
- 种属：Human
- 其他名称：
- Metalloreductase STEAP4 (EC 1.16.1.-) (Six-transmembrane epithelial antigen of prostate 4) (SixTransMembrane protein of prostate 2) (Tumor necrosis factor, alpha-induced protein 9)
- 背景：
- cofactor:FAD.,function:Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.,induction:Up-regulated by androgens, including testosterone and dihydrotestosterone.,similarity:Belongs to the STEAP family.,similarity:Contains 1 ferric oxidoreductase domain.,tissue specificity:Ubiquitous. Highly expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine.,
- 功能：
- transition metal ion transport, ion transport, cation transport, iron ion transport, di-, tri-valent inorganic cation transport, metal ion transport, fat cell differentiation, oxidation reduction,
- 细胞定位：
- Cell membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein . Early endosome membrane ; Multi-pass membrane protein .
- 组织表达：
- Ubiquitous. Highly expressed in adipose tissue. Expressed in placenta, lung, heart and prostate. Detected at lower levels in liver, skeletal muscle, pancreas, testis and small intestine. Highly expressed in joints of patients with rheumatoid arthritis and localized with CD68 cells, a marker for macrophages.
