Total ERK 3 Cell-Based Colorimetric ELISA Kit

  • 货号:KA3769C
  • 应用:ELISA
  • 种属:Human;Mouse;Rat
    • 基因名称:
    • MAPK6
    • Human Gene Id:
    • 5597
    • Human Swiss Prot No:
    • Q16659
    • Mouse Swiss Prot No:
    • Q61532
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • Mitogen-activated protein kinase 6 (MAP kinase 6) (MAPK 6) (EC 2.7.11.24) (Extracellular signal-regulated kinase 3) (ERK-3) (MAP kinase isoform p97) (p97-MAPK)
    • 检测方法:
    • Colorimetric
    • 背景:
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,domain:The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.,enzyme regulation:Activated by threonine and tyrosine phosphorylation.,function:Phosphorylates microtubule-associated protein 2 (MAP2). May promote entry in the cell cycle.,PTM:Dually phosphorylated on Thr-626 and Tyr-628, which activates the enzyme.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.,
    • 功能:
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell cycle,phosphorylation,
    • 细胞定位:
    • Cytoplasm . Nucleus . Translocates to the cytoplasm following interaction with MAPKAPK5. .
    • 组织表达:
    • Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.