Total 3pK Cell-Based Colorimetric ELISA Kit

  • 货号:KA3767C
  • 应用:ELISA
  • 种属:Human;Mouse;Rat
    • 基因名称:
    • MAPKAPK3
    • Human Gene Id:
    • 7867
    • Human Swiss Prot No:
    • Q16644
    • Mouse Swiss Prot No:
    • Q3UMW7
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • MAP kinase-activated protein kinase 3 (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAP-K3) (MAPKAPK-3) (MK-3) (EC 2.7.11.1) (Chromosome 3p kinase) (3pK)
    • 检测方法:
    • Colorimetric
    • 背景:
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Modulator of polycomb-mediated repression, which can be activated either by ERK, p38 and JNK. Substrate of CSBP. In vitro, phosphorylates HSPB1, BMI1/PCGF4 and TCF3.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:Predominantly located in the nucleus, when activated it translocates to the cytoplasm.,subunit:Interacts with TCF3 and with polycomb proteins, such as PCH2 and BMI1/PCGF4.,tissue specificity:Widely expressed, with a higher expression level observed in heart and skeletal muscle. No expression in brain.,
    • 功能:
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, small GTPase mediated signal transduction, Ras protein signal transduction, phosphorylation,
    • 细胞定位:
    • Nucleus . Cytoplasm . Predominantly located in the nucleus, when activated it translocates to the cytoplasm.
    • 组织表达:
    • Widely expressed, with a higher expression level observed in heart and skeletal muscle. No expression in brain. Expressed in the retinal pigment epithelium (PubMed:26744326).