Total 3pK Cell-Based Colorimetric ELISA Kit
- 货号：KA3767C
- 应用：ELISA
- 种属：Human;Mouse;Rat
- 其他名称：
- MAP kinase-activated protein kinase 3 (MAPK-activated protein kinase 3) (MAPKAP kinase 3) (MAPKAP-K3) (MAPKAPK-3) (MK-3) (EC 2.7.11.1) (Chromosome 3p kinase) (3pK)
- 背景：
- catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Modulator of polycomb-mediated repression, which can be activated either by ERK, p38 and JNK. Substrate of CSBP. In vitro, phosphorylates HSPB1, BMI1/PCGF4 and TCF3.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:Predominantly located in the nucleus, when activated it translocates to the cytoplasm.,subunit:Interacts with TCF3 and with polycomb proteins, such as PCH2 and BMI1/PCGF4.,tissue specificity:Widely expressed, with a higher expression level observed in heart and skeletal muscle. No expression in brain.,
- 功能：
- protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, small GTPase mediated signal transduction, Ras protein signal transduction, phosphorylation,
- 细胞定位：
- Nucleus . Cytoplasm . Predominantly located in the nucleus, when activated it translocates to the cytoplasm.
- 组织表达：
- Widely expressed, with a higher expression level observed in heart and skeletal muscle. No expression in brain. Expressed in the retinal pigment epithelium (PubMed:26744326).
