Total Rsk-3 Cell-Based Colorimetric ELISA Kit

  • 货号:KA3746C
  • 应用:ELISA
  • 种属:Human;Mouse
    • 基因名称:
    • RPS6KA2
    • Human Gene Id:
    • 6196
    • Human Swiss Prot No:
    • Q15349
    • Mouse Swiss Prot No:
    • Q9WUT3
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • Ribosomal protein S6 kinase alpha-2 (S6K-alpha-2) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 2) (p90-RSK 2) (p90RSK2) (MAP kinase-activated protein kinase 1c) (MAPK-activated protein kinase 1c) (MAPKAP kinase 1c) (MAPKAPK-1c) (Ribosomal S6 kinase 3) (RSK-3) (pp90RSK3)
    • 检测方法:
    • Colorimetric
    • 背景:
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.,function:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.,PTM:Autophosphorylated on Ser-377, as part of the activation process.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 2 protein kinase domains.,subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation.,tissue specificity:Expressed in many tissues. Highest expression in lung and skeletal muscle.,
    • 功能:
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, protein kinase cascade, phosphorylation,
    • 细胞定位:
    • Nucleus . Cytoplasm .
    • 组织表达:
    • Widely expressed with higher expression in lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate.