Total MB67 Cell-Based Colorimetric ELISA Kit
- 货号：KA3737C
- 应用：ELISA
- 种属：Human
- 其他名称：
- Nuclear receptor subfamily 1 group I member 3 (Constitutive activator of retinoid response) (Constitutive active response) (Constitutive androstane receptor) (CAR) (Orphan nuclear receptor MB67)
- 背景：
- domain:Composed by a short N-terminal domain followed by the DNA binding, hinge, and ligand binding/dimerization domains.,function:Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.,induction:By dexamethasone.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Heterodimer of NR1I3 and RXR. Interacts with PSMC4.,tissue specificity:Predominantly expressed in liver.,
- 功能：
- transcription, regulation of transcription, DNA-dependent, regulation of transcription, regulation of RNA metabolic process,
- 细胞定位：
- Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Recruited to the cytoplasm by DNAJC7. .
- 组织表达：
- Predominantly expressed in liver.
