Total GCKR Cell-Based Colorimetric ELISA Kit
- 货号：KA3729C
- 应用：ELISA
- 种属：Human;Mouse;Rat
- 其他名称：
- Glucokinase regulatory protein (Glucokinase regulator)
- 背景：
- function:Inhibits glucokinase by forming an inactive complex with this enzyme.,similarity:Belongs to the GCKR family.,similarity:Contains 1 SIS domain.,tissue specificity:Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen.,
- 功能：
- protein import into nucleus, translocation, cellular glucose homeostasis, protein targeting, protein import into nucleus,intracellular protein transport, nucleocytoplasmic transport, protein localization, protein transport, protein import,cellular homeostasis, protein localization in organelle, carbohydrate homeostasis, protein localization in nucleus,cellular protein localization, homeostatic process, glucose homeostasis, establishment of protein localization,intracellular transport, chemical homeostasis, nuclear transport, nuclear import, cellular chemical homeostasis, cellular macromolecule localization,
- 细胞定位：
- Cytoplasm . Nucleus . Mitochondrion . Under low glucose concentrations, GCKR associates with GCK and the inactive complex is recruited to the hepatocyte nucleus. .
- 组织表达：
- Found in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen.
