Total N33 Cell-Based Colorimetric ELISA Kit
- 货号：KA3713C
- 应用：ELISA
- 种属：Human;Mouse;Rat
- 其他名称：
- Tumor suppressor candidate 3 (Magnesium uptake/transporter TUSC3) (Protein N33)
- 背景：
- disease:Defects in TUSC3 are the cause of mental retardation non-syndromic autosomal recessive type 7 (MRT7) [MIM:611093]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs.,function:May be involved in N-glycosylation through its association with N-oligosaccharyl transferase.,similarity:Belongs to the OST3/OST6 family.,subunit:Weakly associates with the oligosaccharyl transferase (OST) complex which contains at least RPN1/ribophorin I, RPN2/ribophorin II, OST48, DAD1, and either STT3A or STT3B.,tissue specificity:Expressed in most non-lymphoid cells and tissues examined, including prostate, lung, liver, colon, heart, kidney and pancreas.,
- 功能：
- protein amino acid glycosylation, protein amino acid N-linked glycosylation, glycoprotein metabolic process,glycoprotein biosynthetic process, peptidyl-asparagine modification, protein amino acid N-linked glycosylation via asparagine, biopolymer glycosylation, glycosylation,
- 细胞定位：
- Endoplasmic reticulum membrane ; Multi-pass membrane protein .
- 组织表达：
- Expressed in most non-lymphoid cells and tissues examined, including prostate, lung, liver, colon, heart, kidney and pancreas.
