• 基因名称：
• KLF10/11

• Human Swiss Prot No：
• Q13118/O14901

• 储存：
• 2-8°C/6 months

• 检测方法：
• Colorimetric

• 背景：
• function:Transcriptional repressor involved in the regulation of cell growth. Inhibits cell growth. Binds to the consensus sequence 5'-GGTGTG-3'.,induction:By TGF-beta.,PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,

• 功能：
• negative regulation of transcription from RNA polymerase II promoter, skeletal system development, ossification,regulation of myeloid leukocyte differentiation, positive regulation of myeloid leukocyte differentiation, transcription,regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, induction of apoptosis, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway,transmembrane receptor protein serine/threonine kinase signaling pathway, transforming growth factor beta receptor signaling pathway, cell-cell signaling, cell proliferation, negative regulation of cell proliferation, negative regulation of biosynthetic process, response to organic substance, negative regulation of macromolecule biosynthetic process,negative regulation of macromolecule metabolic process, negative regulation of gene exp

• 细胞定位：
• Nucleus .

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