Total DGK-α Cell-Based Colorimetric ELISA Kit
- 货号：KA3568C
- 应用：ELISA
- 种属：Human
- 其他名称：
- Diacylglycerol kinase alpha (DAG kinase alpha) (EC 2.7.1.107) (80 kDa diacylglycerol kinase) (Diglyceride kinase alpha) (DGK-alpha)
- 背景：
- catalytic activity:ATP + 1,2-diacylglycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate.,enzyme regulation:Stimulated by calcium and phosphatidylserine. Phosphorylated by protein kinase C.,function:Upon cell stimulation converts the second messenger diacylglycerol into phosphatidate, initiating the resynthesis of phosphatidylinositols and attenuating protein kinase C activity.,similarity:Belongs to the eukaryotic diacylglycerol kinase family.,similarity:Contains 1 DAGKc domain.,similarity:Contains 2 EF-hand domains.,similarity:Contains 2 phorbol-ester/DAG-type zinc fingers.,subunit:Monomer.,tissue specificity:Lymphocytes and oligodendroglial cells.,
- 功能：
- cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway, intracellular signaling cascade,regulation of phosphate metabolic process, activation of protein kinase activity, positive regulation of kinase activity,regulation of phosphorylation, positive regulation of catalytic activity, regulation of kinase activity, positive regulation of molecular function, regulation of protein kinase activity, positive regulation of protein kinase activity, regulation of phosphorus metabolic process, regulation of transferase activity, positive regulation of transferase activity,
- 细胞定位：
- Cytoplasm, cytosol .
- 组织表达：
- Expressed in lymphocytes.
