Total SLC43A1 Cell-Based Colorimetric ELISA Kit
- 货号:KA3484C
- 应用:ELISA
- 种属:Human
- 其他名称:
- Large neutral amino acids transporter small subunit 3 (L-type amino acid transporter 3) (Prostate cancer overexpressed gene 1 protein) (Solute carrier family 43 member 1)
- 背景:
- function:Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.,miscellaneous:Up-regulated in early prostate cancer development with highest expression level in seminomas of testicular germ cell tumors.,similarity:Belongs to the SLC43A transporter (TC 2.A.1.44) family.,tissue specificity:In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.,
- 功能:
- amino acid transport, neutral amino acid transport, L-amino acid transport, amine transport, organic acid transport,carboxylic acid transport,
- 细胞定位:
- Membrane ; Multi-pass membrane protein .
- 组织表达:
- In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.