Total SENP1 Cell-Based Colorimetric ELISA Kit
- 货号：KA3414C
- 应用：ELISA
- 种属：Human;Mouse
- 其他名称：
- Sentrin-specific protease 1 (EC 3.4.22.68) (Sentrin/SUMO-specific protease SENP1)
- 背景：
- function:Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. Deconjugates SUMO1 from HIPK2. Deconjugates SUMO1 from HDAC1, which decreases its transcriptional repression activity.,similarity:Belongs to the peptidase C48 family.,subcellular location:Shuttles between cytoplasm and nucleus.,tissue specificity:Highly expressed in testis. Expressed at lower levels in thymus, pancreas, spleen, liver, ovary and small intestine.,
- 功能：
- proteolysis, macromolecule catabolic process, protein desumoylation, modification-dependent protein catabolic process, protein catabolic process, modification-dependent macromolecule catabolic process, cellular protein catabolic process, cellular macromolecule catabolic process, proteolysis involved in cellular protein catabolic process, protein modification by small protein removal, protein modification by small protein conjugation or removal,
- 细胞定位：
- Nucleus . Cytoplasm. Shuttles between cytoplasm and nucleus.
- 组织表达：
- Highly expressed in testis. Expressed at lower levels in thymus, pancreas, spleen, liver, ovary and small intestine.
