Total TRα Cell-Based Colorimetric ELISA Kit
- 货号：KA3395C
- 应用：ELISA
- 种属：Human;Mouse;Rat
- 其他名称：
- Thyroid hormone receptor alpha (Nuclear receptor subfamily 1 group A member 1) (V-erbA-related protein 7) (EAR-7) (c-erbA-1) (c-erbA-alpha)
- 背景：
- domain:Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal steroid-binding domain.,function:Nuclear hormone receptor. High affinity receptor for triiodothyronine.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,subunit:Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Probably interacts with SFPQ. Interacts with C1D (By similarity). Interacts with AKAP13.,
- 功能：
- skeletal system development, cartilage condensation, ossification, transcription, transcription, DNA-dependent,regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, transcription from RNA polymerase II promoter, cell adhesion, intracellular signaling cascade, regulation of heart contraction,response to endogenous stimulus, response to hormone stimulus, hormone-mediated signaling, negative regulation of biosynthetic process, positive regulation of biosynthetic process, response to organic substance, regulation of specific transcription from RNA polymerase II promoter, positive regulation of macromolecule biosynthetic process,negative regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process,negative regulation of macromolecule metabolic process, positive regulation of gene expression, negativ
- 细胞定位：
- Nucleus.; [Isoform Alpha-2]: Cytoplasm . Nucleus . When overexpressed found in the cytoplasm where it colocalizes with TACC1. .
