Total RARβ Cell-Based Colorimetric ELISA Kit
- 货号：KA3370C
- 应用：ELISA
- 种属：Human;Mouse
- 其他名称：
- Retinoic acid receptor beta (RAR-beta) (HBV-activated protein) (Nuclear receptor subfamily 1 group B member 2) (RAR-epsilon)
- 背景：
- domain:Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal steroid-binding domain.,function:This is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression.,similarity:Belongs to the nuclear hormone receptor family.,similarity:Belongs to the nuclear hormone receptor family. NR1 subfamily.,similarity:Contains 1 nuclear receptor DNA-binding domain.,
- 功能：
- negative regulation of transcription from RNA polymerase II promoter, eye development, urogenital system development, metanephros development, ureteric bud development, kidney development, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, sensory organ development, heart development, muscle organ development, negative regulation of cell proliferation, negative regulation of biosynthetic process, positive regulation of biosynthetic process, positive regulation of macromolecule biosynthetic process, negative regulation of macromolecule biosynthetic process, positive regulation of macromolecule metabolic process, negative regulation of macromolecule metabolic process, positive regulation of gene expression,negative regulation of gene expression, regulation of cell death, positive regulation of cell death, striated muscle
- 细胞定位：
- Nucleus . Cytoplasm .; [Isoform Beta-1]: Nucleus.; [Isoform Beta-2]: Nucleus.; [Isoform Beta-4]: Cytoplasm.
- 组织表达：
- Expressed in aortic endothelial cells (at protein level).
