Total Nck-2 Cell-Based Colorimetric ELISA Kit
- 货号：KA3336C
- 应用：ELISA
- 种属：Human;Mouse
- 其他名称：
- Cytoplasmic protein NCK2 (Growth factor receptor-bound protein 4) (NCK adaptor protein 2) (Nck-2) (SH2/SH3 adaptor protein NCK-beta)
- 背景：
- function:Adapter protein which associates with tyrosine-phosphorylated growth factor receptors or their cellular substrates. Maintains low levels of EIF2S1 phosphorylation by promoting its dephosphorylation by PP1.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 SH3 domains.,similarity:Contains 3 SH3 domains.,subunit:Interacts with DOCK1, PINCH and TGFB1I1. Part of a complex containing PPP1R15B, PP1 and NCK2.,tissue specificity:Ubiquitous.,
- 功能：
- cell activation, positive regulation of immune system process, regulation of leukocyte activation, positive regulation of leukocyte activation, regulation of translation, protein complex assembly, cell motion, cytoskeleton organization, actin filament organization, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, signal complex assembly, epidermal growth factor receptor signaling pathway, regulation of epidermal growth factor receptor activity, regulation of actin polymerization or depolymerization, positive regulation of cell proliferation, negative regulation of cell proliferation,regulation of receptor activity, posttranscriptional regulation of gene expression, positive regulation of organelle organization, cell migration, regulation of phosphate metabolic process, act
- 细胞定位：
- Cytoplasm . Endoplasmic reticulum .
