Total MMP-8 Cell-Based Colorimetric ELISA Kit

  • 货号：KA3334C
  • 应用：ELISA
  • 种属：Human;Mouse;Rat
    • 基因名称：
    • MMP8
    • Human Gene Id：
    • 4317
    • Human Swiss Prot No：
    • P22894
    • Mouse Swiss Prot No：
    • O70138
    • 储存：
    • 2-8°C/6 months
    • 其他名称：
    • Neutrophil collagenase (EC 3.4.24.34) (Matrix metalloproteinase-8) (MMP-8) (PMNL collagenase) (PMNL-CL)
    • 检测方法：
    • Colorimetric
    • 背景：
    • catalytic activity:Cleavage of interstitial collagens in the triple helical domain. Unlike EC 3.4.24.7, this enzyme cleaves type III collagen more slowly than type I.,cofactor:Binds 2 zinc ions per subunit.,cofactor:Binds 3 calcium ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,enzyme regulation:Cannot be activated without removal of the activation peptide.,function:Can degrade fibrillar type I, II, and III collagens.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 4 hemopexin-like domains.,subcellular location:Stored in intracellular granules.,tissue specificity:Neutrophils.,
    • 功能：
    • skeletal system development, ossification, proteolysis, collagen catabolic process, collagen metabolic process,multicellular organismal metabolic process, multicellular organismal catabolic process, multicellular organismal macromolecule metabolic process, bone development,
    • 细胞定位：
    • Cytoplasmic granule. Secreted, extracellular space, extracellular matrix . Stored in intracellular granules.
    • 组织表达：
    • Neutrophils.

    相关报价

    • 货号：
    • KA3334C
    • 规格：
    • 96 / well
    • 价格：
    • ¥3300
    • 货期：
    • 预计发货时间为
      2024-08-03
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