Phospho CRMP2 (T509) Cell-Based Colorimetric ELISA Kit
- 货号:KA1746C
- 应用:ELISA
- 种属:Human;Mouse;Rat
- 基因名称:
- DPYSL2
- Human Gene Id:
- 1808
- Human Swiss Prot No:
- Q16555
- Mouse Swiss Prot No:
- O08553
- Rat Swiss Prot No:
- P47942
- 储存:
- 2-8°C/6 months
- 其他名称:
- Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (N2A3) (Unc-33-like phosphoprotein 2) (ULIP-2)
- 检测方法:
- Colorimetric
- 背景:
- function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.,PTM:3F4, a monoclonal antibody which strongly stains neurofibrillary tangles in Alzheimer disease brains, specifically labels DPYSL2 when phosphorylated on Ser-518, Ser-522 and Thr-509.,similarity:Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.,subunit:Homotetramer, and heterotetramer with CRMP1, DPYSL3, DPYSL4 or DPYSL5 (By similarity). Interacts through its C-terminus with the C-terminus of CYFIP1/SRA1. Interacts with HTR4.,tissue specificity:Ubiquitous.,
- 细胞定位:
- Cytoplasm, cytosol . Cytoplasm, cytoskeleton . Membrane . Tightly but non-covalently associated with membranes.
- 组织表达:
- Ubiquitous.
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