Phospho Claudin 3 (Y219) Cell-Based Colorimetric ELISA Kit

  • 货号:KA1743C
  • 应用:ELISA
  • 种属:Human
    • 基因名称:
    • CLDN3
    • Human Gene Id:
    • 1365
    • Human Swiss Prot No:
    • O15551
    • Mouse Swiss Prot No:
    • Q9Z0G9
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • Claudin-3 (Clostridium perfringens enterotoxin receptor 2) (CPE-R 2) (CPE-receptor 2) (Rat ventral prostate.1 protein homolog) (hRVP1)
    • 检测方法:
    • Colorimetric
    • 背景:
    • disease:Haploinsufficiency of CLDN3 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS), a rare developmental disorder. It is a contiguous gene deletion syndrome involving genes from chromosome band 7q11.23.,function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,subunit:Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.,
    • 功能:
    • response to hypoxia, cell adhesion, cell-cell adhesion, calcium-independent cell-cell adhesion, biological adhesion,response to oxygen levels,
    • 细胞定位:
    • Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein .