• 基因名称：
• MSN

• Human Swiss Prot No：
• P26038/P35241/P15311

• 储存：
• 2-8°C/6 months

• 检测方法：
• Colorimetric

• 背景：
• function:Probably involved in connections of major cytoskeletal structures to the plasma membrane.,PTM:Phosphorylation on Thr-558 is crucial for the formation of microvilli-like structures.,similarity:Contains 1 FERM domain.,subcellular location:Phosphorylated form is enriched in microvilli-like structures at apical membrane.,subunit:In resting T-cells, part of a PAG1-SLC9A3R1-MSN complex which is disrupted upon TCR activation (By similarity). Binds SLC9A3R1.,tissue specificity:In all tissues and cultured cells studied.,

• 功能：
• cell motion, cell adhesion, leukocyte adhesion, cell-cell adhesion, cell migration, membrane docking, biological adhesion, membrane to membrane docking, cell motility, leukocyte migration, localization of cell,

• 细胞定位：
• Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton . Apical cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, microvillus membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, microvillus . Phosphorylated form is enriched in microvilli-like structures at apical membrane. Increased cell membrane localization of both phosphorylated and non-phosphorylated forms seen after thrombin treatment (By similarity). Localizes at the uropods of T lymphoblasts. .

• 组织表达：
• In all tissues and cultured cells studied.

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