Phospho RFA2 (T21) Cell-Based Colorimetric ELISA Kit

  • 货号：KA1472C
  • 应用：ELISA
  • 种属：Human;Mouse
    • 基因名称：
    • RFA2
    • Human Gene Id：
    • 6118
    • Human Swiss Prot No：
    • P15927
    • Mouse Swiss Prot No：
    • Q62193
    • 储存：
    • 2-8°C/6 months
    • 其他名称：
    • Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
    • 检测方法：
    • Colorimetric
    • 背景：
    • function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,
    • 功能：
    • nucleotide-excision repair, DNA damage removal, DNA metabolic process, DNA replication, DNA-dependent DNA replication, DNA repair, nucleotide-excision repair, nucleotide-excision repair, DNA gap filling, DNA catabolic process,response to DNA damage stimulus, macromolecule catabolic process, cellular response to stress, cellular macromolecule catabolic process,
    • 细胞定位：
    • Nucleus . Nucleus, PML body . Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner. .

    相关报价

    • 货号：
    • KA1472C
    • 规格：
    • 96 / well
    • 价格：
    • ¥4700
    • 货期：
    • 预计发货时间为
      2024-12-07
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