Phospho GRK1 (S21) Cell-Based Colorimetric ELISA Kit

  • 货号：KA1462C
  • 应用：ELISA
  • 种属：Human;Mouse;Rat
    • 基因名称：
    • GRK1
    • Human Gene Id：
    • 6011
    • Human Swiss Prot No：
    • Q15835
    • Mouse Swiss Prot No：
    • Q9WVL4
    • 储存：
    • 2-8°C/6 months
    • 其他名称：
    • Rhodopsin kinase (RK) (EC 2.7.11.14) (G protein-coupled receptor kinase 1)
    • 检测方法：
    • Colorimetric
    • 背景：
    • catalytic activity:ATP + [rhodopsin] = ADP + [rhodopsin] phosphate.,disease:Defects in GRK1 are a cause of congenital stationary night blindness Oguchi type (CSNBO) [MIM:258100]; also known as Oguchi disease. Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision. CSNBO is an autosomal recessive form associated with fundus discoloration and abnormally slow dark adaptation.,function:Phosphorylates rhodopsin thereby initiating its deactivation.,online information:Retina International's Scientific Newsletter,PTM:Autophosphorylated.,PTM:Farnesylation is required for full activity.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 RGS domain.,tissue specificity:Retina and pineal gland.,
    • 功能：
    • cell morphogenesis, cell morphogenesis involved in differentiation, eye development, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, apoptosis, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, sensory organ development, sensory perception, visual perception, phototransduction, phototransduction, visible light, cell death, regulation of G-protein coupled receptor protein signaling pathway, photoreceptor cell morphogenesis, response to radiation, response to light stimulus, detection of external stimulus, detection of abiotic stimulus, detection of light stimulus, detection of visible light, rhodopsin mediated phototransduction, response to abiotic stimulus, post-embryonic development, post-embryonic morphogenesis, positive regulation of phosphorus metabolic process, programmed cell death,
    • 细胞定位：
    • Membrane ; Lipid-anchor . Cell projection, cilium, photoreceptor outer segment . Subcellular location is not affected by light or dark conditions. .
    • 组织表达：
    • Retinal-specific. Expressed in rods and cones cells.

    相关报价

    • 货号：
    • KA1462C
    • 规格：
    • 96 / well
    • 价格：
    • ¥4700
    • 货期：
    • 预计发货时间为
      2024-08-01
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