Phospho DAPP1 (Y139) Cell-Based Colorimetric ELISA Kit

  • 货号:KA1449C
  • 应用:ELISA
  • 种属:Human;Mouse
    • 基因名称:
    • DAPP1
    • Human Swiss Prot No:
    • Q9UN19
    • Mouse Swiss Prot No:
    • Q9QXT1
    • 储存:
    • 2-8°C/6 months
    • 其他名称:
    • Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (hDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa)
    • 检测方法:
    • Colorimetric
    • 背景:
    • function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.,induction:Upon B-cell activation.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH2 domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation.,subunit:Interacts with PtdIns(3,4,5)P3 and PLCG2. In vitro, interacts with PtdIns(3,4)P2.,tissue specificity:Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.,
    • 功能:
    • protein amino acid dephosphorylation, phosphorus metabolic process, phosphate metabolic process,dephosphorylation,
    • 细胞定位:
    • Cytoplasm . Membrane ; Peripheral membrane protein . Membrane-associated after cell stimulation leading to its translocation.
    • 组织表达:
    • Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.