Phospho B-Myb (S577/581) Cell-Based Colorimetric ELISA Kit
- 货号:KA1425C
- 应用:ELISA
- 种属:Human;Mouse;Rat
- 基因名称:
- MYBL2
- Human Gene Id:
- 4605
- Human Swiss Prot No:
- P10244
- Mouse Swiss Prot No:
- P48972
- 储存:
- 2-8°C/6 months
- 其他名称:
- Myb-related protein B (B-Myb) (Myb-like protein 2)
- 检测方法:
- Colorimetric
- 背景:
- function:Transcription factor involved in the regulation of cell survival, proliferation, and differentiation. Transactivates the expression of the CLU gene.,PTM:Phosphorylated by cyclin A/CDK2 during S-phase. Phosphorylation at Thr-520 is probably involved in transcriptional activity.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Component of the DREAM complex (also named LINC complex) at least composed of E2F4, E2F5, LIN9, LIN37, LIN52, LIN54, MYBL1, MYBL2, RBL1, RBL2, RBBP4, TFDP1 and TFDP2. The complex exists in quiescent cells where it represses cell cycle-dependent genes. It dissociates in S phase when LIN9, LIN37, LIN52 and LIN54 form a subcomplex that binds to MYBL22.,
- 功能:
- transcription, regulation of transcription,
- 细胞定位:
- Nucleus.
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