Phospho MYB (S12) Cell-Based Colorimetric ELISA Kit
- 货号:KA1304C
- 应用:ELISA
- 种属:Human;Mouse
- 基因名称:
- MYB
- Human Gene Id:
- 4602
- Human Swiss Prot No:
- P10242
- Mouse Swiss Prot No:
- P06876
- 储存:
- 2-8°C/6 months
- 其他名称:
- Transcriptional activator Myb (Proto-oncogene c-Myb)
- 检测方法:
- Colorimetric
- 背景:
- domain:Comprised of 3 domains; an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression.,function:Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.,PTM:Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.,PTM:Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Binds MYBBP1A. Interacts with HIPK2, MAF and NLK.,
- 功能:
- transcription, regulation of transcription, DNA-dependent, regulation of transcription, regulation of RNA metabolic process,
- 细胞定位:
- Nucleus .
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