Phospho Calnexin (S583) Cell-Based Colorimetric ELISA Kit
- 货号:KA1271C
- 应用:ELISA
- 种属:Human;Mouse;Rat
- 基因名称:
- CANX
- Human Gene Id:
- 821
- Human Swiss Prot No:
- P27824
- Mouse Swiss Prot No:
- P35564
- Rat Swiss Prot No:
- P35565
- 储存:
- 2-8°C/6 months
- 其他名称:
- Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
- 检测方法:
- Colorimetric
- 背景:
- function:Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.,online information:Calnexin entry,similarity:Belongs to the calreticulin family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
- 功能:
- protein folding, protein localization, protein secretion, protein transport, secretion by cell, establishment of protein localization, secretion,
- 细胞定位:
- Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232). .
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