Phospho Csk (S364) Cell-Based Colorimetric ELISA Kit

  • 货号：KA1241C
  • 应用：ELISA
  • 种属：Human;Mouse;Rat
    • 基因名称：
    • CSK
    • Human Gene Id：
    • 1445
    • Human Swiss Prot No：
    • P41240
    • Mouse Swiss Prot No：
    • P41241
    • 储存：
    • 2-8°C/6 months
    • 其他名称：
    • Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-Src kinase) (Protein-tyrosine kinase CYL)
    • 检测方法：
    • Colorimetric
    • 背景：
    • catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Specifically phosphorylates 'Tyr-504' on LCK, which acts as a negative regulatory site. Can also act on the LYN and FYN kinases.,PTM:Autophosphorylation of Tyr-304 occurs only at abnormally high CSK concentrations in vitro.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,similarity:Contains 1 SH3 domain.,subcellular location:Mainly cytoplasmic, also present in lipid rafts.,subunit:Interacts with PTPN8 (By similarity). Interacts with phosphorylated SIT1, PAG1, LIME1 and TGFB1I1.,tissue specificity:Expressed in lung and macrophages.,
    • 功能：
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, negative regulation of cell proliferation, phosphorylation, regulation of cell proliferation,
    • 细胞定位：
    • Cytoplasm . Cell membrane . Mainly cytoplasmic, also present in lipid rafts. .
    • 组织表达：
    • Expressed in lung and macrophages.

    相关报价

    • 货号：
    • KA1241C
    • 规格：
    • 96 / well
    • 价格：
    • ¥4700
    • 货期：
    • 预计发货时间为
      2024-08-01
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