• Purity：
• >90% as determined by SDS-PAGE

• Gene Name：
• Sp7 / Osterix

• Protein Name：
• Transcription factor Sp7 (Zinc finger protein osterix)

• Sequence：
• Amino acid:25-170,with rabbit FC tag.

• Human Gene Id：
• 121340

• Human Swiss Prot No：
• Q8TDD2

• Formulation：
• Phosphate-buffered solution

• Source：
• Mammalian cells

• Storage Stability：
• -15°C to -25°C/1 year(Avoid freeze / thaw cycles)

• Background：
• This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010],

• Function：
• function:Transcriptional activator essential for osteoblast differentiation. Binds to Sp1 and EKLF consensus sequences and to other G/C-rich sequences.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,

• Subcellular Location：
• Nucleus .

• Expression：
• Restricted to bone-derived cell.

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