TBR1 rabbit-FC recombinant protein
- Catalog No.:YD3130
- Reactivity:Human;
- Purity:
- >90% as determined by SDS-PAGE
- Protein Name:
- T-box brain protein 1 (T-brain-1) (TBR-1) (TES-56)
- Sequence:
- Amino acid:1-196,with rabbit FC tag.
- Formulation:
- Phosphate-buffered solution
- Storage Stability:
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- Background:
- This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of numerous developmental processes. In mouse, the ortholog of this gene is expressed in the cerebral cortex, hippocampus, amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection. In mouse, the C-terminal region of this protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq, Dec 2015],
- Function:
- function:Probable transcriptional regulator involved in developmental processes. TBR1 is required for normal brain development.,similarity:Contains 1 T-box DNA-binding domain.,tissue specificity:Brain.,
- Subcellular Location:
- Nuclear