Hepatocyte-FC recombinant protein
- Catalog No.:YD3038
- Reactivity:Human;
- Purity:
- >90% as determined by SDS-PAGE
- Protein Name:
- Hepatocyte growth factor (Hepatopoietin-A) (Scatter factor) (SF) [Cleaved into: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain]
- Sequence:
- Amino acid:495-728,with FC tag.
- Formulation:
- Phosphate-buffered solution
- Storage Stability:
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- Other Name:
- Hepatocyte growth factor ;Hepatopoietin-A;Scatter factor;SF; ;HGF;HPTA;
- Function:
- Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types (PubMed:20624990). Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (PubMed:15167892, PubMed:20977675). Activates MAPK signaling following TMPRSS13 cleavage and activation (PubMed:20977675).