CEA (carcinoembryonic antigen)-FC recombinant protein

  • Catalog No.：YD3023
  • Reactivity：Human;
    • Purity：
    • >90% as determined by SDS-PAGE
    • Gene Name：
    • CEACAM5
    • Protein Name：
    • Carcinoembryonic antigen-related cell adhesion molecule 5 (Carcinoembryonic antigen) (CEA) (Meconium antigen 100) (CD antigen CD66e)
    • Sequence：
    • Amino acid:35-314,with FC tag.
    • Human Gene Id：
    • 1048
    • Human Swiss Prot No：
    • P06731
    • Formulation：
    • Phosphate-buffered solution
    • Source：
    • Mammalian cells
    • Storage Stability：
    • -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
    • Other Name：
    • Carcinoembryonic antigen-related cell adhesion molecule 5 ;Carcinoembryonic antigen;CEA;Meconium antigen 100;CD antigen CD66e;CEACAM5;CEA;
    • Function：
    • Cell surface glycoprotein that plays a role in cell adhesion, intracellular signaling and tumor progression (PubMed:10864933, PubMed:10910050, PubMed:2803308). Mediates homophilic and heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6 (PubMed:2803308). Plays a role as an oncogene by promoting tumor progression; induces resistance to anoikis of colorectal carcinoma cells (PubMed:10910050).; (Microbial infection) Receptor for E.coli Dr adhesins. Binding of E.coli Dr adhesins leads to dissociation of the homodimer.
    • Subcellular Location：
    • Cell membrane ; Lipid-anchor, GPI-anchor . Apical cell membrane . Cell surface . Note=Localized to the apical glycocalyx surface. .
    • Expression：
    • Expressed in columnar epithelial and goblet cells of the colon (at protein level) (PubMed:10436421). Found in adenocarcinomas of endodermally derived digestive system epithelium and fetal colon.

    Attributes

    • Code：
    • YD3023
    • Size
    • 5μg / 50μg / 500μg
    • Price$：
    • 52 / 272 / 1356
    • Delivery：
    • 2024-11-23
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