KLRG1 (MAFA)-FC recombinant protein
- Catalog No.：YD3004
- Reactivity：Human;
- Purity：
- >90% as determined by SDS-PAGE
- Protein Name：
- Killer cell lectin-like receptor subfamily G member 1 (C-type lectin domain family 15 member A) (ITIM-containing receptor MAFA-L) (MAFA-like receptor) (Mast cell function-associated antigen)
- Sequence：
- Amino acid:60-195,with FC tag.
- Formulation：
- Phosphate-buffered solution
- Storage Stability：
- -15°C to -25°C/1 year(Avoid freeze / thaw cycles)
- Other Name：
- Killer cell lectin-like receptor subfamily G member 1 ;C-type lectin domain family 15 member A;ITIM-containing receptor MAFA-L;MAFA-like receptor;Mast cell function-associated antigen;KLRG1;CLEC15A;MAFA;MAFAL;
- Function：
- Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
- Subcellular Location：
- Cell membrane ; Single-pass type II membrane protein .
- Expression：
- Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.
