Phospho ETK (Y40) Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA1364C
  • Applications：ELISA
  • Reactivity：Human;Mouse
    • Gene Name：
    • BMX
    • Human Gene Id：
    • 660
    • Human Swiss Prot No：
    • P51813
    • Mouse Swiss Prot No：
    • P97504
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Cytoplasmic tyrosine-protein kinase BMX (EC 2.7.10.2) (Bone marrow tyrosine kinase gene in chromosome X protein) (Epithelial and endothelial tyrosine kinase) (ETK) (NTK38)
    • Detection Method：
    • Colorimetric
    • Background：
    • catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,cofactor:Binds 1 zinc ion per subunit.,domain:SH2 domain mediates interaction with RUFY1.,function:Activity is required for interleukin 6 (IL-6) induced differentiation. May play a role in the growth and differentiation of hematopoietic cells. May be involved in signal transduction in endocardial and arterial endothelial cells.,induction:Activated by IL-6 through phosphatidylinositol 3-kinase (PI3-kinase) pathway. It is likely that activation occurs through binding of phosphoinositides to the PH domain.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.,similarity:Contains 1 Btk-type zinc finger.,similarity:Contains 1 PH domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH2 domain.,subunit:Interacts with RUFY1 and RUFY2.,tissue specificity:Preferentially expressed in epithelial and endothelial cells.,
    • Function：
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, mesoderm development, phosphorylation,
    • Subcellular Location：
    • Cytoplasm . Localizes to the edges of spreading cells when complexed with BCAR1.
    • Expression：
    • Highly expressed in cells with great migratory potential, including endothelial cells and metastatic carcinoma cell lines.

    Attributes

    • Code：
    • KA1364C
    • Size
    • 96 / well
    • Price$：
    • 470
    • Delivery：
    • 2024-12-11
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