Primary immunodeficiency
Primary immunodeficiencies (PIs) are a heterogeneous group of disorders, which affect cellular and humoral immunity or non-specific host defense mechanisms mediated by complement proteins, and cells such as phagocytes and natural killer (NK) cells. These disorders of the immune system cause increased susceptibility to infection, autoimmune disease, and malignancy. Most of PIs are due to genetic defects that affect cell maturation or function at different levels during hematopoiesis. Disruption of the cellular immunity is observed in patients with defects in T cells or both T and B cells. These cellular immunodeficiencies comprise 20% of all PIs. Disorders of humoral immunity affect B-cell differentiation and antibody production. They account for 70% of all PIs.
Product List
- ADA Rabbit pAbHuman,Rat,Mouse,WB,ELISA
- IL-7R Rabbit pAbHuman,Mouse,MonkeyWB,ELISA
- IL-7R (Phospho Tyr449) Rabbit pAbHuman,MouseWB,IF,ELISA
- IL-7R/CD127 (Phospho Tyr449) Cell-Based Colorimetric ELISA KitHuman,MouseELISA
- IL-2Rγ Rabbit pAbHuman,MouseWB,ELISA
- JAK3 (PT0405R) PT® Rabbit mAbHuman,WB,IF,IP,ELISA
- JAK3 (6B5) Mouse mAbHuman,Mouse,RatIHC
- JAK3 Rabbit pAbHuman,Mouse,RatWB,IHC,IF,ELISA
- JAK3 (Phospho Tyr785) Rabbit pAbHuman,Mouse,RatWB,IHC,IF,ELISA
- Jak3 (Phospho Tyr980/981) Rabbit pAbHuman,MouseWB,IHC
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