Prolactin (PRL) is a polypeptide hormone known to be involved in a wide range of biological functions including osmoregulation, lactation, reproduction, growth and development, endocrinology and metabolism, brain and behavior, and immunomodulation. PRL mediates its action through PRLR, a transmembrane protein of the hematopoietin cytokine receptor superfamily. At the protein level, the long PRLR isoform (long-R) and several short PRLR isoforms (short-R) have been detected. Acting through the long-R, PRL activates many signaling cascades including Jak2/Stat, the major cascade, Src kinase, phosphatidylinositol-3-kinase (PI3K)/AKT, and mitogen-activated protein kinase (MAPK) pathways. PRL cannot activate Jak2/Stat5 through the short-R, but can activate pathways including MAPK and PI3K pathways.
Product List
Catalog
Product
Reactivity
Applications
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Prolactin (ABT-PRL) Mouse mAb
Human,
IHC,IF,ELISA
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Prolactin (ABT220) Mouse mAb
Human,
IHC,IF,ELISA
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Prolactin (ABT-PRL) Mouse mAb (Ready to Use)
Human,
IHC
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Prolactin (ABT220) Mouse mAb (Ready to Use)
Human,
IHC
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Prolactin Rabbit pAb
Human,Rat,Mouse,
WB,IHC,IF,ELISA
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Mouse PRL(Prolactin) ELISA Kit
Mouse
ELISA
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Rat PRL(Prolactin) ELISA Kit
Rat
ELISA
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Prolactin (ABT-PRL) IHC kit
Human,
IHC
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Prolactin (ABT220) IHC kit
Human,
IHC
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PRLR Rabbit pAb
Human
WB,ELISA