P2RX7 rabbit pAb

  • 货号:YT8119
  • 应用:IHC;WB
  • 种属:Human;Mouse;Rat
    • 靶点:
    • P2RX7
    • 基因名称:
    • P2RX7
    • 蛋白名称:
    • P2X purinoceptor 7 (P2X7) (ATP receptor) (P2Z receptor) (Purinergic receptor)
    • Human Gene Id:
    • 5027
    • Human Swiss Prot No:
    • Q99572
    • Mouse Swiss Prot No:
    • Q9Z1M0
    • 免疫原:
    • Synthesized peptide derived from human C-ternal P2RX7
    • 特异性:
    • This antibody detects endogenous levels of P2RX7 at Human, Mouse,Rat
    • 组成:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • 来源:
    • Polyclonal, Rabbit,IgG
    • 稀释:
    • WB 1:500-2000 IHC 1:50-200
    • 纯化工艺:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 其他名称:
    • P2X purinoceptor 7 (P2X7) (ATP receptor) (P2Z receptor) (Purinergic receptor)
    • 分子量:
    • 65kD
    • 功能:
    • Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells .
    • 细胞定位:
    • Cell membrane ; Multi-pass membrane protein .
    • 组织表达:
    • Widely expressed with highest levels in brain and immune tissues.