PANX1 rabbit pAb

  • 货号:YT8118
  • 应用:IHC;WB
  • 种属:Human;Mouse;Rat
    • 靶点:
    • PANX1
    • 基因名称:
    • PANX1 MRS1 UNQ2529/PRO6028
    • 蛋白名称:
    • Pannexin-1
    • Human Swiss Prot No:
    • Q96RD7
    • Mouse Swiss Prot No:
    • Q9JIP4
    • 免疫原:
    • Synthesized peptide derived from human C-ternal PANX1
    • 特异性:
    • This antibody detects endogenous levels of PANX1 at Human, Mouse,Rat
    • 组成:
    • Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
    • 来源:
    • Polyclonal, Rabbit,IgG
    • 稀释:
    • WB 1:500-2000 IHC 1:50-200
    • 纯化工艺:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 其他名称:
    • Pannexin-1
    • 分子量:
    • 47kD
    • 功能:
    • Structural component of the gap junctions and the hemichannels involved in the ATP release and nucleotide permeation . May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis . Plays a critical role in oogenesis .
    • 细胞定位:
    • Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction . Endoplasmic reticulum membrane ; Multi-pass membrane protein .
    • 组织表达:
    • Widely expressed (PubMed:30918116). Highest expression is observed in oocytes and brain (PubMed:30918116). Detected at very low levels in sperm cells (PubMed:30918116).