• 靶点：
• CUL9

• 基因名称：
• CUL9 H7AP1 KIAA0708 PARC

• 蛋白名称：
• Cullin-9 (CUL-9) (UbcH7-associated protein 1) (p53-associated parkin-like cytoplasmic protein)

• Human Gene Id：
• 23113

• Human Swiss Prot No：
• Q8IWT3

• Mouse Swiss Prot No：
• Q80TT8

• 免疫原：
• Synthesized peptide derived from human C-ternal CUL9

• 特异性：
• This antibody detects endogenous levels of CUL9 at Human, Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000 IHC 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• Cullin-9 (CUL-9) (UbcH7-associated protein 1) (p53-associated parkin-like cytoplasmic protein)

• 分子量：
• 277kD

• 功能：
• Core component of a Cul9-RING ubiquitin-protein ligase complex, a complex that mediates ubiquitination and subsequent degradation of BIRC5 and is required to maintain microtubule dynamics and genome integrity. Acts downstream of the 3M complex, which inhibits CUL9 activity, leading to prevent ubiquitination of BIRC5 . Cytoplasmic anchor protein in p53/TP53-associated protein complex. Regulates the subcellular localization of p53/TP53 and subsequent function .

• 细胞定位：
• Cytoplasm .

• 组织表达：
• Ubiquitously expressed in all tissues with highest expression in testis brain and kidney.

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