OPTN rabbit pAb

  • 货号：YT8007
  • 应用：WB
  • 种属：Human;Mouse;Rat
    • 靶点：
    • OPTN
    • 简介：
    • >>Mitophagy - animal;>>Amyotrophic lateral sclerosis;>>Pathways of neurodegeneration - multiple diseases
    • 基因名称：
    • OPTN FIP2 GLC1E HIP7 HYPL NRP
    • 蛋白名称：
    • OPTN
    • Human Swiss Prot No：
    • Q96CV9
    • Mouse Swiss Prot No：
    • Q8K3K8
    • 免疫原：
    • Synthesized peptide derived from human OPTN
    • 特异性：
    • This antibody detects endogenous levels of OPTN at Human, Mouse,Rat
    • 组成：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • 来源：
    • Polyclonal, Rabbit,IgG
    • 稀释：
    • WB 1:500-2000
    • 纯化工艺：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度：
    • 1 mg/ml
    • 储存：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 其他名称：
    • Optineurin (E3-14.7K-interacting protein) (FIP-2) (Huntingtin yeast partner L) (Huntingtin-interacting protein 7) (HIP-7) (Huntingtin-interacting protein L) (NEMO-related protein) (Optic neuropathy-inducing protein) (Transcription factor IIIA-interacting protein) (TFIIIA-IntP)
    • 分子量：
    • 63kD
    • 细胞定位：
    • Cytoplasm, perinuclear region. Golgi apparatus . Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle, autophagosome. Cytoplasmic vesicle. Recycling endosome. Found in the perinuclear region and associates with the Golgi apparatus (PubMed:27534431). Colocalizes with MYO6 and RAB8 at the Golgi complex and in vesicular structures close to the plasma membrane. Localizes to LC3-positive cytoplasmic vesicles upon induction of autophagy. .
    • 组织表达：
    • Present in aqueous humor of the eye (at protein level). Highly expressed in trabecular meshwork. Expressed nonpigmented ciliary epithelium, retina, brain, adrenal cortex, fetus, lymphocyte, fibroblast, skeletal muscle, heart, liver, brain and placenta.

    相关报价

    • 货号：
    • YT8007
    • 规格：
    • 40μL / 100μL / 200μL
    • 价格：
    • ¥960 / 2300 / 3780
    • 货期：
    • 预计发货时间为
      2024-12-23
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