QIK/QSK rabbit pAb

  • 货号:YT7998
  • 应用:WB
  • 种属:Human;Mouse;Rat
    • 靶点:
    • QIK/QSK
    • 简介:
    • >>Glucagon signaling pathway
    • 基因名称:
    • SIK2 KIAA0781 QIK SNF1LK2
    • 蛋白名称:
    • QIK/QSK
    • Human Swiss Prot No:
    • Q9H0K1
    • Mouse Swiss Prot No:
    • Q8CFH6
    • 免疫原:
    • Synthesized peptide derived from human QIK/QSK
    • 特异性:
    • This antibody detects endogenous levels of QIK/QSK at Human, Mouse,Rat
    • 组成:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • 来源:
    • Polyclonal, Rabbit,IgG
    • 稀释:
    • WB 1:500-2000
    • 纯化工艺:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 其他名称:
    • Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2)
    • 实测条带:
    • 105kD
    • 功能:
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,subunit:Interacts with and phosphorylates TORC2/CRTC2.,
    • 细胞定位:
    • Cytoplasm . Endoplasmic reticulum membrane .
    • 组织表达:
    • Brain,Colon,Lung,Testis,