• 靶点：
• SWS

• 基因名称：
• OPN1SW BCP

• 蛋白名称：
• SWS

• Human Gene Id：
• 611

• Human Swiss Prot No：
• P03999

• Mouse Gene Id：
• 12057

• Mouse Swiss Prot No：
• P51491

• Rat Gene Id：
• 81644

• Rat Swiss Prot No：
• Q63652

• 免疫原：
• Synthesized peptide derived from human SWS

• 特异性：
• This antibody detects endogenous levels of Human SWS

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 其他名称：
• Short-wave-sensitive opsin 1 (Blue cone photoreceptor pigment;Blue-sensitive opsin;BOP)

• 实测条带：
• 38kD

• 背景：
• This gene belongs to the G-protein coupled receptor 1 family, opsin subfamily. It encodes the blue cone pigment gene which is one of three types of cone photoreceptors responsible for normal color vision. Defects in this gene are the cause of tritan color blindness (tritanopia). Affected individuals lack blue and yellow sensory mechanisms while retaining those for red and green. Defective blue vision is characteristic. [provided by RefSeq, Jul 2008],

• 功能：
• disease:Defects in OPN1SW are the cause of tritan color blindness (tritanopia) [MIM:190900].,function:Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal.,online information:Retina International's Scientific Newsletter,PTM:Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.,tissue specificity:The three color pigments are found in the cone photoreceptor cells.,

• 细胞定位：
• Cell membrane ; Multi-pass membrane protein . Photoreceptor inner segment . Cell projection, cilium, photoreceptor outer segment . Cytoplasm, perinuclear region .

• 组织表达：
• The three color pigments are found in the cone photoreceptor cells (PubMed:2937147). Expressed throughout the epidermis and dermis, primarily in the stratum granulosum in the facial and abdominal skin (at protein level) (PubMed:30168605). Expressed in dermal fibroblasts (at protein level) (PubMed:31380578). Expressed in melanocytes (at protein level) (PubMed:31730232).

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