AGRP rabbit pAb

  • 货号:YT7889
  • 应用:WB;ELISA
  • 种属:Human;Mouse
    • 靶点:
    • AGRP
    • 简介:
    • >>Adipocytokine signaling pathway
    • 基因名称:
    • AGRP AGRT ART
    • 蛋白名称:
    • AGRP
    • Human Gene Id:
    • 181
    • Human Swiss Prot No:
    • O00253
    • Mouse Swiss Prot No:
    • P56473
    • 免疫原:
    • Synthesized peptide derived from human AGRP
    • 特异性:
    • This antibody detects endogenous levels of Human,Mouse AGRP
    • 组成:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • 来源:
    • Polyclonal, Rabbit,IgG
    • 稀释:
    • WB 1:1000-2000 ELISA 1:5000-20000
    • 纯化工艺:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 其他名称:
    • Agouti-related protein
    • 分子量:
    • 15kD
    • 背景:
    • disease:Defects in AGRP may be a cause of autosomal dominant obesity [MIM:601665].,domain:The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin.,function:Plays a role in weight homeostasis. May play a role in the regulation of melanocortin receptors within the hypothalamus and adrenal gland, and therefore in the central control of feeding.,similarity:Contains 1 agouti domain.,tissue specificity:Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.,
    • 功能:
    • cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, neuropeptide signaling pathway, intracellular signaling cascade, behavior, feeding behavior, adult feeding behavior, response to endogenous stimulus, response to hormone stimulus, hormone-mediated signaling, response to organic substance,adult behavior, cellular response to hormone stimulus, eating behavior,
    • 细胞定位:
    • Secreted . Golgi apparatus lumen .
    • 组织表达:
    • Expressed primarily in the adrenal gland, subthalamic nucleus, and hypothalamus, with a lower level of expression occurring in testis, lung, and kidney.