Claudin-18 rabbit pAb

  • 货号:YT7850
  • 应用:WB;ELISA
  • 种属:Human;Rat;Mouse;
    • 靶点:
    • Claudin 18
    • 简介:
    • >>Cell adhesion molecules;>>Tight junction;>>Leukocyte transendothelial migration;>>Pathogenic Escherichia coli infection;>>Hepatitis C
    • 基因名称:
    • CLDN18 UNQ778/PRO1572
    • 蛋白名称:
    • Claudin-18
    • Human Swiss Prot No:
    • P56856
    • Mouse Swiss Prot No:
    • P56857
    • 免疫原:
    • Synthesized peptide derived from human Claudin-18. AA:70-100
    • 特异性:
    • This antibody detects endogenous levels of Human Claudin-18
    • 组成:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • 来源:
    • Polyclonal, Rabbit,IgG
    • 稀释:
    • WB 1:1000-2000 ELISA 1:5000-20000
    • 纯化工艺:
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度:
    • 1 mg/ml
    • 储存:
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 其他名称:
    • Claudin-18
    • 分子量:
    • 29kD
    • 功能:
    • function:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.,similarity:Belongs to the claudin family.,tissue specificity:Concentrated at the cell-cell borders of epithelial cells.,
    • 细胞定位:
    • Cell junction, tight junction . Cell membrane ; Multi-pass membrane protein . Localizes to tight junctions in epithelial cells. .
    • 组织表达:
    • Isoform A1: Expression is restricted to the lung (PubMed:19047087). Isoform A2: Expression is restricted to the stomach mucosa where it is predominantly observed in the epithelial cells of the pit region and the base of the gastric glands including exocrine and endocrine cells (at protein level) (PubMed:19047087).