CD94 rabbit pAb

  • 货号：YT7838
  • 应用：WB;ELISA
  • 种属：Human;Rat;Mouse;
    • 靶点：
    • CD94
    • 简介：
    • >>Antigen processing and presentation;>>Natural killer cell mediated cytotoxicity;>>Graft-versus-host disease
    • 基因名称：
    • KLRD1 CD94
    • 蛋白名称：
    • CD94
    • Human Gene Id：
    • 3824
    • Human Swiss Prot No：
    • Q13241
    • Mouse Swiss Prot No：
    • O54707
    • 免疫原：
    • Synthesized peptide derived from human CD94 AA range: 124-173
    • 特异性：
    • This antibody detects endogenous levels of Human CD94
    • 组成：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • 来源：
    • Polyclonal, Rabbit,IgG
    • 稀释：
    • WB 1:1000-2000 ELISA 1:5000-20000
    • 纯化工艺：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • 浓度：
    • 1 mg/ml
    • 储存：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • 其他名称：
    • Natural killer cells antigen CD94 (KP43;Killer cell lectin-like receptor subfamily D member 1;NK cell receptor;CD antigen CD94)
    • 分子量：
    • 20kD
    • 背景：
    • Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
    • 功能：
    • function:Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.,online information:CD94,similarity:Contains 1 C-type lectin domain.,subunit:Can form disulfide-bonded heterodimer with NKG2 family members.,tissue specificity:Natural killer cells.,
    • 细胞定位：
    • Cell membrane ; Single-pass type II membrane protein .
    • 组织表达：
    • Expressed in NK cell subsets (at protein level) (PubMed:21825173, PubMed:9430220, PubMed:9485206). Expressed in memory/effector CD8-positive alpha-beta T cell subsets (at protein level) (PubMed:12387742, PubMed:20952657). Expressed in melanoma-specific cytotoxic T cell clones (at protein level) (PubMed:9485206). Expressed in terminally differentiated cytotoxic gamma-delta T cells (at protein level) (PubMed:20952657). KLRD1-KLRC1 and KLRD1-KLRC2 are differentially expressed in NK and T cell populations, with only minor subsets expressing both receptor complexes (at protein level) (PubMed:20952657).

    相关报价

    • 货号：
    • YT7838
    • 规格：
    • 40μL / 100μL / 200μL
    • 价格：
    • ¥960 / 2300 / 3780
    • 货期：
    • 预计发货时间为
      2024-11-23
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