• 靶点：
• CMBL

• 简介：
• >>Metabolic pathways

• 基因名称：
• CMBL

• 蛋白名称：
• CMBL

• Human Gene Id：
• 134147

• Human Swiss Prot No：
• Q96DG6

• Mouse Gene Id：
• 69574

• Mouse Swiss Prot No：
• Q8R1G2

• Rat Gene Id：
• 310201

• Rat Swiss Prot No：
• Q7TP52

• 免疫原：
• Synthesized peptide derived from human CMBL AA range: 136-186

• 特异性：
• This antibody detects endogenous levels of CMBL at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 27kD

• 背景：
• CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010],

• 功能：
• similarity:Belongs to the dienelactone hydrolase family.,

• 细胞定位：
• Cytoplasm, cytosol .

• 组织表达：
• Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level).

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