• 靶点：
• SELH

• 基因名称：
• SELH C11orf31

• 蛋白名称：
• SELH

• Human Gene Id：
• 280636

• Human Swiss Prot No：
• Q8IZQ5

• Mouse Gene Id：
• 72657

• Mouse Swiss Prot No：
• Q3UQA7

• 免疫原：
• Synthesized peptide derived from human SELH AA range: 58-108

• 特异性：
• This antibody detects endogenous levels of SELH at Human/Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 13kD

• 背景：
• This gene encodes a nucleolar protein, which belongs to the SelWTH family. It functions as an oxidoreductase, and has been shown to protect neurons against UVB-induced damage by inhibiting apoptotic cell death pathways, promote mitochondrial biogenesis and mitochondrial function, and suppress cellular senescence through genome maintenance and redox regulation. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2016],

• 功能：
• function:May be involved in a redox-related process .,similarity:Belongs to the SelWTH family.,

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