HSF2B rabbit pAb

    • 货号:YT7552
    • 应用:WB
    • 种属:Human;Mouse
      • 靶点:
      • HSF2B
      • 基因名称:
      • HSF2BP
      • 蛋白名称:
      • HSF2B
      • Human Swiss Prot No:
      • O75031
      • 免疫原:
      • Synthesized peptide derived from human HSF2B AA range: 201-251
      • 特异性:
      • This antibody detects endogenous levels of HSF2B at Human
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 37kD
      • 背景:
      • HSF2 binding protein (HSF2BP) associates with HSF2. The interaction occurs between the trimerization domain of HSF2 and the amino terminal hydrophilic region of HSF2BP that comprises two leucine zipper motifs. HSF2BP may therefore be involved in modulating HSF2 activation. [provided by RefSeq, Jul 2008],
      • 功能:
      • function:May be involved in modulating HSF2 activation in testis.,PTM:Sumoylated by UBE2I in response to MEKK1-mediated stimuli.,subunit:Associates with HSF2. The interaction seems to occur between the trimerization domain of HSF2 and the N-terminal hydrophilic region of HSF2BP.,tissue specificity:Testis specific.,
      • 细胞定位:
      • Cytoplasm . Chromosome . Localizes on double-strand breaks (DSBs) in mitotic and meiotic chromosomes. .
      • 组织表达:
      • Testis specific. Overexpressed in some tumors (PubMed:31242413).
      • 产品图片
      • Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night