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WB 试剂
- PonceauS Staining Solution
- PBST Washing Buffer, 10X
- 1.5M Tris-HCl Buffer, pH8.8
- 1M Tris-HCl Buffer, pH6.8
- 10% SDS Solution
- Prestained Protein Marker
- TBST Washing Buffer, 10X
- SDS PAGE Loading Buffer, 5X
- Stripping Buffered Solution
- Tris Buffer, pH7.4, 10X
- Total Protein Extraction Kit
- Running Buffer, 10X
- Transfer Buffer, 10X
- 30% Acr-Bis(29:1) Solution
- Tris电泳液速溶颗粒
- PBS(1X, premixed powder)
- TBS(1X, premixed powder)
- 快速封闭液
- 转膜液速溶颗粒
- Chemical reagents
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GLYM rabbit pAb
- 货号:YT7523
- 应用:WB
- 种属:Human;Mouse
- 简介:
- >>Glycine, serine and threonine metabolism;>>Glyoxylate and dicarboxylate metabolism;>>One carbon pool by folate;>>Metabolic pathways;>>Carbon metabolism;>>Biosynthesis of amino acids;>>Biosynthesis of cofactors;>>Antifolate resistance
- 免疫原:
- Synthesized peptide derived from human GLYM AA range: 122-172
- 特异性:
- This antibody detects endogenous levels of GLYM at Human
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 背景:
- This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
- 功能:
- catalytic activity:5,10-methylenetetrahydrofolate + glycine + H(2)O = tetrahydrofolate + L-serine.,cofactor:Pyridoxal phosphate.,function:Interconversion of serine and glycine.,miscellaneous:In eukaryotes there are two forms of the enzymes: a cytosolic one and a mitochondrial one.,pathway:One-carbon metabolism; tetrahydrofolate pathway.,similarity:Belongs to the SHMT family.,subunit:Homotetramer.,
- 细胞定位:
- Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid . Mitochondrion inner membrane . Cytoplasm . Nucleus . Mainly localizes in the mitochondrion. Also found in the cytoplasm and nucleus as part of the BRISC complex (PubMed:24075985). .
![](/uploadfiles/PIC/YT7523wb-2019.jpg)
- Western blot analysis of lysates from A549 cells, primary antibody was diluted at 1:1000, 4°over night