• 靶点：
• NUDT9

• 简介：
• >>Purine metabolism;>>Metabolic pathways

• 基因名称：
• NUDT9 NUDT10 PSEC0099 UNQ3012/PRO9771

• 蛋白名称：
• NUDT9

• Human Gene Id：
• 53343

• Human Swiss Prot No：
• Q9BW91

• Mouse Gene Id：
• 74167

• Mouse Swiss Prot No：
• Q8BVU5

• Rat Gene Id：
• 305149

• Rat Swiss Prot No：
• Q5XIG0

• 免疫原：
• Synthesized peptide derived from human NUDT9 AA range: 107-157

• 特异性：
• This antibody detects endogenous levels of NUDT9 at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 39kD

• 背景：
• The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011],

• 功能：
• catalytic activity:ADP-ribose + H(2)O = AMP + D-ribose 5-phosphate.,cofactor:Magnesium.,cofactor:Manganese.,function:Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'-phosphate.,induction:Isoform 1 is inhibited by fluoride and N-acetyl-p-benzoquinoneimine.,similarity:Belongs to the Nudix hydrolase family. NudF subfamily.,subunit:Monomer. Interacts with C17orf25.,tissue specificity:Ubiquitously expressed but isoform 1 is the most predominant isoform.,

• 细胞定位：
• [Isoform 1]: Mitochondrion.

• 组织表达：
• Ubiquitously expressed but isoform 1 is the most predominant isoform.

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