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WB 试剂
- PonceauS Staining Solution
- PBST Washing Buffer, 10X
- 1.5M Tris-HCl Buffer, pH8.8
- 1M Tris-HCl Buffer, pH6.8
- 10% SDS Solution
- Prestained Protein Marker
- TBST Washing Buffer, 10X
- SDS PAGE Loading Buffer, 5X
- Stripping Buffered Solution
- Tris Buffer, pH7.4, 10X
- Total Protein Extraction Kit
- Running Buffer, 10X
- Transfer Buffer, 10X
- 30% Acr-Bis(29:1) Solution
- Tris电泳液速溶颗粒
- PBS(1X, premixed powder)
- TBS(1X, premixed powder)
- 快速封闭液
- 转膜液速溶颗粒
- Chemical reagents
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PCD19 rabbit pAb
- 货号:YT7422
- 应用:WB;IHC
- 种属:Human;Mouse
- 免疫原:
- Synthesized peptide derived from human PCD19 AA range: 841-891
- 特异性:
- This antibody detects endogenous levels of PCD19 at Human/Mouse
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000;IHC 1:50-300
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 背景:
- The protein encoded by this gene is a member of the delta-2 protocadherin subclass of the cadherin superfamily. The encoded protein is thought to be a calcium-dependent cell-adhesion protein that is primarily expressed in the brain. Defects in this gene are a cause of epilepsy female-restricted with mental retardation (EFMR). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010],
- 功能:
- developmental stage:Expressed in developing cortical plate, amygdala and subcortical regions and in the ganglionic eminence.,disease:Defects in PCDH19 are the cause of epilepsy, female-restricted, with mental retardation (EFMR) [MIM:300088]; also known as convulsive disorder and mental retardation. EFMR is a condition characterized by seizure onset in infancy or early childhood and cognitive impairment. The disorder is sex-limited, with the phenotype being restricted to females. Males are apparently spared.,function:Potential calcium-dependent cell-adhesion protein.,similarity:Contains 6 cadherin domains.,tissue specificity:Moderately expressed in all regions of the brain examined, with lowest levels found in the cerebellum. Moderate expression is also found in ovary, and low expression in all other tissues tested. Also detected in primary skin fibroblast.,
- 细胞定位:
- Cell membrane ; Single-pass type I membrane protein .
- 组织表达:
- Moderately expressed in all regions of the brain examined, with lowest levels found in the cerebellum. Moderate expression is also found in ovary, and low expression in all other tissues tested. Also detected in primary skin fibroblast.
![](/uploadfiles/PIC/YT7422wb-2019.jpg)
- Western blot analysis of lysates from HuvEc cells, primary antibody was diluted at 1:1000, 4°over night
![](/uploadfiles/PIC/31ruanxianaicc.jpg)
- Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).