• 靶点：
• TM55A

• 简介：
• >>Phosphatidylinositol signaling system

• 基因名称：
• TMEM55A

• 蛋白名称：
• TM55A

• Human Gene Id：
• 55529

• Human Swiss Prot No：
• Q8N4L2

• Mouse Gene Id：
• 72519

• Mouse Swiss Prot No：
• Q9CZX7

• Rat Gene Id：
• 362490

• Rat Swiss Prot No：
• Q4V888

• 免疫原：
• Synthesized peptide derived from human TM55A AA range: 33-83

• 特异性：
• This antibody detects endogenous levels of TM55A at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 28kD

• 背景：
• TMEM55A catalyzes the degradation of phosphatidylinositol 4,5-bisphosphate (PtdIns-4,5-P2) by removing the 4-phosphate (Ungewickell et al., 2005 [PubMed 16365287]).[supplied by OMIM, Mar 2008],

• 功能：
• catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate.,catalytic activity:1-phosphatidyl-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate.,function:Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate.,tissue specificity:Ubiquitous.,

• 细胞定位：
• Late endosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, phagosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .

• 组织表达：
• Ubiquitous.

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