• 靶点：
• FMT

• 简介：
• >>One carbon pool by folate;>>Aminoacyl-tRNA biosynthesis;>>Metabolic pathways

• 基因名称：
• MTFMT FMT FMT1

• 蛋白名称：
• FMT

• Human Gene Id：
• 123263

• Human Swiss Prot No：
• Q96DP5

• Mouse Gene Id：
• 69606

• Mouse Swiss Prot No：
• Q9D799

• Rat Gene Id：
• 315763

• Rat Swiss Prot No：
• Q5I0C5

• 免疫原：
• Synthesized peptide derived from human FMT AA range: 115-165

• 特异性：
• This antibody detects endogenous levels of FMT at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 43kD

• 背景：
• The protein encoded by this nuclear gene localizes to the mitochondrion, where it catalyzes the formylation of methionyl-tRNA. [provided by RefSeq, Jun 2011],

• 功能：
• catalytic activity:10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) + H(2)O = tetrahydrofolate + N-formylmethionyl-tRNA(fMet).,domain:Composed of an N- and a C-terminal domain. The N-terminal domain carries the tetrahydrofolate (THF)-binding site and the C-terminal domain is presumably involved in positioning the Met-tRNA substrate for the formylation reaction.,function:Formylates methionyl-tRNA in mitochondria. A single tRNA(Met) gene gives rise to both an initiator and an elongator species via an unknown mechanism.,similarity:Belongs to the fmt family.,

• 细胞定位：
• Mitochondrion .

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